A laboratory scale device for microencapsulation of genetically engineered cells into alginate beads
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Keywords

CHO cells
interleukin-2
protein delivery

How to Cite

1.
Fiszman GL, Karara AL, Finocchiaro LME, Glikin GC. A laboratory scale device for microencapsulation of genetically engineered cells into alginate beads. Electron. J. Biotechnol. [Internet]. 2002 Dec. 15 [cited 2024 Sep. 19];5(3):0-. Available from: https://preprints.pucv.cl/index.php/ejbiotechnology/article/view/v5n3-5

Abstract

The microencapsulation of recombinant cells, widely used for in vitro high-density cell culture, is a novel and potentially cost-effective method of in vivo heterologous protein delivery, where the protein producing cells are immunologically protected from tissue rejection. We report here a simple, reliable and inexpensive laboratory method to generate calcium alginate microcapsules containing genetically engineered, interleukin-2 expressing, Chinese hamster ovary (CHO) cells.

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